Evaluation of Mixtures: Interpretation of Results and Prediction of Effects in Humans
نویسنده
چکیده
The prediction of a biological effect of a mixture of chemicals in man, from animal experiments, is much facilitated when the biochemical basis of interactions is known. Several examples of materials encountered in the workplace and of drugs are given which support this thesis. It is also known that species extrapolation, in general, is less accurate for a mixture than for a single chemical; in some (rare) cases it is even impossible.
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تاریخ انتشار 2006